pennatifolius) is a source of pilocarpine.
It is a native of Brazil. The word 'Jaborandi' is an
word meaning slobber weed because ingestion of the plant
intense salivation. The natives use the plant to induce
Jaborandi leaves was first introduced to western medicine
by Symphronio Coutinho, a Brazilian physician.
Initially the plant
was used to treat dry mouth because of its ability to
salivation. The active ingredient of Jaborandi is the
pilocarpine which mimic the action of acetylcholine,
neurotransmitter of the parasympathetic system. Topical
was first introduced in 1877 to reduce the intraocular
works by reducing the resistance to aqueous outflow through
stimulation of the iris sphincter and the ciliary muscle.
effects are miosis and accommodation spasm with associated