Jaborandi (Pilocarpus pennatifolius) is a source of pilocarpine.
It is a native of Brazil. The word 'Jaborandi' is an Amazonian Indian 
word meaning slobber weed because ingestion of the plant causes 
intense salivation. The natives use the plant to induce sweating. 
Jaborandi leaves was first introduced to western medicine in 1873, 
by  Symphronio Coutinho, a Brazilian physician. Initially the plant 
was used to treat dry mouth because of its ability to induce 
salivation. The active ingredient of Jaborandi is the alkaloid 
pilocarpine which mimic the action of acetylcholine, the primary
neurotransmitter of the parasympathetic system. Topical pilocarpine
was first introduced in 1877 to reduce the intraocular pressure. It
works by reducing the resistance to aqueous outflow through
stimulation of the iris sphincter and the ciliary muscle. The resulting
effects are miosis and accommodation spasm with associated