Plants with ocular effects: 4
USA (1993 SG2775)

Physostigmine is an anti-cholinesterase derived from calabar bean (also

known as ordeal bean see Ophthalmic Kew Garden). It was first isolated
by Fraser in 1864. In ophthalmic practise, it was used to reduce intraocular
pressure by increasing the aqueous outflow via pupil constriction. Percy
Lavon Julian, an American chemist is the first to synthesize physostigmine.
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