Plants with Ocular Effects
East Germany
Yugoslavia (1961 SG1000)
Digitalis used in cardiac failure and cardiac arrhythmia is derived from the plant foxgloves. The man credited with the introduction of digitalis into the practice of medicine was William Withering. Withering was born in Wellington, Shropshire, England in 1741. Toxic doses can give rise to ocular effects which include colour vision abnormalities (most patients complain of seeing yellow colour, xanthopsia), visual sensations and hallucinations, scotomas and retinal toxicity with abnormal ERG amplitudes. The great Dutch painter was thought to suffer from digitalis poisoning because of his predominant use of yellow paint. He had epilepsy and was treated with digitalis which was commonly used to control seizure.
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