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Berry aneurysms are thought to be due to congenital absence of the media
and internal elastic lamina with ballooning as the blood pulsates through
the vessels over the years.
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Ruptures occur when an area becomes thinned and there is a period of hypertension
or straining.,
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Berry aneurysms are found incidentally at autopsy 1-2% of the time.
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Aneurysms occur in the anterior Circle of Willis 80% of the time. The Anterior
communicating artery and middle cerebral artery at the trifurcation are
the most common sites of origin.
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