Dosages of anti-metabolites for trabeculectomy
  • 25-50mg/ml.
  • cellulose sponge is cut into small pieces and soaked in the solution
  • apply the sponge in the under surface of the conjunctiva (Tenon's capsule) at the site of future bleb. 
  • apply in total 3 sponges for 3 minutes ie. one sponge for each minute
  • irrigate the applied area with about 30 ml of normal saline
Mitomycin C
  • 0.2-0.4 mg/ml
  • use sponge and apply for 3 minutes as for 5-FU
  • irrigate the applied area copiously with about 30ml of normal saline.
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