Squamous papilloma of the eyelid is the most common benign lesion. Clinically it appears pedunculated or sessile with finger-like projection on its surface. Unlike conjunctival papilloma, most squamous papilloma is not associated with viral infection.

A squamous papilloma in the lower lid margin.

Histologically, the following features are present:

• epithelial acanthosis and hyperkeratosis with folds that surround a central fibrovascular core.

Squamous papilloma at  low magnification.

Squamous papilloma at higher magnification showing the finger-like  projection and the central fibrovascular cord.

Common question:

• How does squamous papilloma differ from viral papilloma? (In viral papilloma, there is inflammatory hypertrophy of papillae with viral inclusions.)