Persistent hyperplastic primary vitreous (PHPV)
 
 

This is a rare unilateral condition. Most cases seen in the  examination will be of the less severe form. Less commonly  you may have a patient with leukocoria and microphthalmos. The picture seen here is of the posterior type of PHPV. The  optic disc contains dense, white fibrous tissue extending towards  the ora serrata (usually inferiorly). The retinal vessels are distorted  as they emerge from the optic disc. Further examination: posterior PHPV may resemble retinopathy of prematurity  with dragged disc. In retinopathy of prematurity, a ridge  is usually seen in the periphery the patient may have microphthalmos ± esotropia

Questions:

1. Which conditions may simulate PHPV?

Answer
retinoblastoma
retinopathy of prematurity
toxocariasis

2. What are the complications of PHPV?

Answer
cataract
secondary angle closure glaucoma
retinal detachment
vitreous haemorrhage

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