This 65 year-old woman complains of an area of distortion near her left central vision. Examination reveals an elevated area below the left optic disc. A fluorescein angiography is performed and is as shown above.

a. What does the angiography show?

b. What is the diagnosis?

 

Answer to a
The fluorescein angiography shows progressive pooling within a lesion which is constant in size. 
 

Answer to bA retinal pigment epithelium detachment. 
In retinal pigment epithelium detachment, the lesion tends to remain
the same size despite progressive hyperfluorescence. In subretinal
lesion, the hyperfluorescence will progressively increase in size as in
central serious retinopathy. These differences can be explained by 
the much stronger adhesion between the Bruch's membrane and the RPE than between the retina and the RPE