The macula contains well circumscribed, rounded macular lesion measuring about 1 to 2 disc diameter. The lesion
contains yellowish substance show at the inferior half of the lesion (pseudohypopyon). The condition is bilateral
(although the macula may show different stages of Best's disease).
Note: Best's disease evolves through five stages. Most patients are over the age of 20 have vitelliform eruptive or
- look outside the macula for smaller lesion
end stages. The end stage may be indistinguishable from age-related macular degeneration. In young patient with
macular atrophy or fibrosis always consider Best disease in your differential diagnosis.
1. How is Best's disease inherited?