This man has multiple lesions on his face and trunks. His family
members also have similar lesions.
a. What does the histology show?
Palisading of tumour cells. This is typical of basal cell carcinoma.
b. What is the diagnosis?
Gorlin's syndrome (basal cell naevus syndrome).
This is a rare autosomal dominant characterised by multiple basal
cell carcinoma early in life. The systemic features include: jaw cysts,
skeletal anomalies and ectopic calcification.
c. What is the prognosis of this condition?
Normal life expectancy is common. The basal cell carcinoma
early treatment to avoid disfiguring scars.