Test 40 (microbiology)
1. The following are true about tetanus acquired through traumatic wound:
a. the diagnosis is depends on microbial findings

b. Clostridium tetani travels via the nerves to the anterior horn 
    cells in the spinal cord

c. the tetanospasmin component of the exotoxin acts on the 
    post-synaptic neurones and prevents impulse transmission.

d. the patient should be given antitoxin intravenously

e. the presence of Clostridium tetani in the wound can be 
    identified by a positive Nagler reaction

2. Hepatitis B virus:

a. is a DNA virus

b. the presence of e antigen indicates increased infectivity

c. antibody to surface antigen usually appears within 2 weeks 
    of infection

d. the carrier rate is about 0.1% in the UK

e. is a recognized cause of liver cancer


3. The following drugs act by inhibiting cell wall synthesis of the 
a. vancomycin

b. gentamicin

c. cefuroxime

d. amphotericin B

e. erythromycin.


4. The Mantoux test:
a. is positive in all patients with tuberculosis

b. involves injecting PPD (purified protein derivative) 

c. is more sensitive than the tine test

d. becomes positive within 3 weeks of acquiring tuberculosis

e. involves the CD4 cells


5. The following are true about Pseudomonas aeruginosa:
a. it is the most common cause of contact lens acquired 

b. it is a Gram negative bacteria

c. it can cause osteomyelitis

d. it is sensitive to chloramphenicol

e. it is sensitive to ciprofloxacin


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