Past Part 1 MRCOphth: 14
1. Diamox:
a. is excreted unchanged in urine
b. is concentrated in iris and ciliary epithelium
c. works in alkaline environment
d. crystallized in renal tubules
e. increases the respiratory rate
2. Systemic b-blocker:
a. should be avoided in patients on verapamil
b. decreases intraocular pressure
c. increases the effect of potassium supplement
d. can be given even if the patient is on topical b-blocker
e. causes dry eye

3. Aqueous:

a. has a lower sodium concentration in the anterior than posterior chamber
b. has a refractive index of 1.336
c. has a volume of about 1 ml in the anterior chamber
d. supplements most of the nutrients to the corneal epithelium
e. has an ascorbic acid concentration which is 5 times that of the serum

4. Regarding the photoreceptor outer segment:

a. the cone pigments differ in opsin
b. phagocytosis occurs only in the rod outer segment 
c. abnormal phagocytosis of RPE is a cause of some forms of retinitis pigmentosa
d. phagocytosis of the rod outer segment is increased in darkness
e. there are joined together by tight junctions
5. The following are known components of cataract:
a. urate
b. haemosiderosis
c. oxalate crystals
d. calcium phosphate
e. creatinine crystals

6. Cholesterol crystals are found in:

a. subretinal space in Coat's disease
b. lipid keratopathy
c. disciform macular degeneration
d. lattice degeneration
e. synchysis scintillans

7. Morphea basal cell carcinoma:

a. is cystic
b. has a later presentation than the nodular form
c. has a higher recurrence rate after excision biopsy
d. contains pallasading of cells
e. contains fibrosis in the surrounding tissue

8. Optic chiasm:

a. is anterior to the olfactory bulb
b. in albinism has decrease crossing of fibres
c. has a variable relationship to the pituitary gland
d. supplied by anterior communicating artery
e. forms part of the wall of the third ventricle
9. Regarding CMV virus:
a. it is a RNA virus
b. it belongs to the same family as Epstein-Barr virus
c. it is sensitive to acyclovir
d. it rarely caused retinitis in HIV patients with normal CD4+ counts
e. it causes foetal abnormalities if the mother acquires the infection during pregnancy

10. The following are causes of hyperviscosity syndrome:

a. iron deficiency anaemia
b. multiple myeloma
c. hyperlipidaemia
d. sickle cell anaemia
e. haemorrhagic shock
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