Past Part 1 MRCOphth: 10
1. Craniopharyngioma:
a. arises from the pituitary gland
b. calcification is common
c. generally fast growing
d. majority presents before age 30
e. may cause compression of the optic chiasm

2. The following are autosomal dominant:

a. myotonic dystrophica
b. Wyburn-Mason syndrome
c. Sturge-Weber syndrome
d. neurofibromatosis
e. keratoconus

3. Tetanus:

a. is caused by an anaerobic bacillus
b. has an incubation period of less than 48 hours
c. results in life long immunity
d. is associated with hypercatabolic state
e. occurs only after major trauma

4. The neutrophil polymorph:

a. originate in the bone marrow
b. destroys bacteria predominantly by anaerobic mechanism
c. show mitotic activity when engaged in inflammatory reaction
d. is the effector cell in the destruction of virus
e. is the characteristic cell of granulomatous inflammation
5. In relation to osmotic diuretic in treatment of glaucoma:
a. glycerol is a small size molecule, administered orally and is rapidly 
b. mannitol has rapid action but poor ocular penetration
c. mannitol is rapidly excreted in the urine and may cause cerebrovascular 
d. urea can be used as an osmotic diuretic in the treatment of glaucoma
e. mannitol must be warmed before use to dissolve crystals that may have 
6. The following cell types have a phagocytic function:
a. tissue histiocytes
b. microglia
c. small lymphocytes
d. Kupffer cell
e. neutrophil polymorphs
7. Chemotactic factors:
a. increase directional leukocyte movement
b. active macrophage
c. decrease C3b receptors on phagocytes
d. have a long half life
e. interact with specific membrane receptor

8. The following are seen in healing after a clean surgical incision:

a. regeneration of epithelium
b. granulation tissue formation
c. massive necrosis
d. antibodies production locally
e. migration of microglia.

9. The following statement(s) is/are correct:

a. sterilization implies the destruction or removal of pathogenic organism so 
    as to render the object non-infective
b. boiling (1000C for 5 minutes) kills all vegetative organism and spores
c. the ultraviolet light produced artificially hs powerful germicidal properties
d. halogen in very low concentration kill bacteria, virus, fungi and spores
e. ether has little antibacterial properties.

10. Staphylococcus aureus:

a. lives as a commensal on the anterior nasal mucosa of 30-50% of general 
b. antibodies against staphylococcus aureus are present in the serum of all 
    normal people
c. Staphylococcal food poisoning is due to consumption of preformed 
    exotoxin in food
d. are coagulase-negative organisms
e. produce a heat labile nuclease.
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