Test 192  (Ocular pharmacology)
1. The side effects of pilocarpine include:
a. dry eye

b. increased sweating

c. bronchiolar spasm

d. increased salivation

e. constipation


2. The following are true about pilocarpine:

a. it increases the concentration of acetylcholine in the 
    synaptic cleft

b. it increases trabeulcar meshwork outflow but 
    decreases uveoscleral outflow

c. patients with dark iris are more sensitive to the miotic 
    effect of pilocarpine

d. it increases the depth of focus

e. it induces myopia by increasing the axial length of the 


3. Pilocarpine is contraindicated in the following conditions:
a. malignant glaucoma

b. pseudoexfoliation glaucoma

c. hypertensive uveitis

d. aphakic glaucoma

e. subacute angle closure glaucoma

. 4. With regard to the effect of atropine:
a. mydriasis is the result of paralysis of the constrictor 
    muscle of the pupil

b. mydriasis occurs more rapidly than cycloplegia

c. cycloplegia persists longer than mydriasis

d. it causes forward movement of the lens

e. it causes a breakdown in the blood aqueous barrier

5. The following are true with regard to acetazolamide: 

a. 99% of carbonic anhydrase must be inhibited before 
    there is an effect on the intraocular pressure

b. it increases rate of subretinal fluid absorption between 
    retina and retinal pigment epithelium

c. it reduces the rate of aqueous production by up to 50%

d. a solution of acetazolamide has an alkaline pH 

e. it is excreted unchanged by the kidneys

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