Test 162  (Biochemistry )
1. With regard to collagen molecule:
a. it is formed from trimers

b. it is formed from polypeptides containing a chains

c. glycine accounts for one-third of amino acids found
    within collagens

d. it contains less hydroxyproline than elastin

e. ascorbate is essential for hydroxylation of proline 


2. Type I collagen:
a. contains two a1 chains and one a2 chain

b. is the most common collagen

c. is the main type of collagen found in basement 

d. is found in skin and bone

e. is found in cornea 

3. Elastin:
a. is synthesized only by the liver

b. contains cross-linking polypeptides involving lysine

c. is the most common connective tissue in lungs

d. is digested by a1-antitrypsin

e. can be stretched to several times its length and can 
    still return to its original shape.


4. Vitamin B12:

a. is fat-soluble

b. requires a glycoprotein from absorption

c. contains a haeme ring

d. is required for the conversion of homocysteine to 

e. is need for myelination of nerve fibres


5. In mucopolysaccharidoses:
a. the production of proteoglycan is increased

b. proteoglycan degradation is reduced

c. the lysosomal enzyme is defective

d. the urine excretes excess oligosaccharides

e. the body has an increased accumulation of 

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