a. contain antigen-binding sites derived from both the
heavy and light chains.
b. contains Fc regions derived solely from the heavy
c. are chiefly of Ig E class at mucosal surfaces
d. are produced by both T and B lymphocytes
e. of Ig E class give protection against parasitic worms.
a. is mediated by complement components.
b. enhances phagocytosis
c. involves mainly the Fc protion of the immunoglobulins
d. involves fibronectin
e. is not restricted by the MHC (Major Histocompatiblity
a. has a molecular weight of 50,000 kd.
b. is monvalent
c. comprises the majority of circulating antibody in serum
d. differs from other isotypes in being ablt to cross the
e. is the major antibody produced during the primary
4. For antigen presentation to CD4+ T lymphocytes:
a. antigen is processed via the endogenous pathway
b. specialised antigen presenting cells are required for the
induction of the T cell immune response
c. Short antigen-derived peptides associate with MHC
class II molecules in the endoplasmic reticulum
d. exogenously added synthetic peptide corresponding to
the antigenic epitope can substitute for processed
antigen for T cell recognition.
e. the antigen must be synthesised within the antigen
presenting cell in order to be processed and presented
5. In the thymus:
a. the majority of cortical thymocytes express either CD4
b. CD4/CD8 double positive cells are eliminated by a
process of negative selection.
c. a proportion of alpha/beta+ thymocytes undergo
isotype switching to produce gamma/delta+ T cells.
d. thymocytes whose TcR bind with high affinity to self
Ag/MHC complexes are clonally detected.
e. mature thymocytes express surface IgM and IgD